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Cordocentesis

Cordocentesis

Cordocentesis is performed to determine whether the baby has been exposed to infection or has a genetic problem while in the womb.

What is Cordocentesis?

Cordocentesis is the process of taking a blood sample of the baby from the umbilical cord between the baby and the mother under ultrasound guidance. Performed after the 20th week, this procedure provides information about the baby's genetic health.

If it is thought that the baby has any chromosomal anomaly or gene mutation, cordocentesis can be applied in pregnancies of 20 or more weeks with the decision of the obstetrician. Cordocentesis, a diagnostic test, gives 99.9% accurate results regarding the health of the baby.

Why is Cordocentesis Performed?

If there is any risk factor in your cordocentesis pregnancy;

  • Age risk (+35)
  • Fetal USG abnormality findings
  • Indication for prenatal diagnosis at advanced gestational week
  • Developmental delay in the baby
  • Detection of risk in other screening tests
  • Parental carriage of chromosomal irregularities
  • Parental carriage of a single gene disease (such as SMA)
  • Detection of an anomaly in fetal DNA testing from maternal blood (the result must be confirmed by prenatal diagnostic methods)
  • History of chromosomal disease in previous pregnancies
  • Anxiety (request for prenatal testing because the family is worried)

If you have even one of these, you can find out whether your baby is genetically healthy with cordocentesis.

How is cordocentesis performed?

A specialist perinatologist takes a blood sample of the baby from the mother's abdomen, using a special needle and ultrasonography.

A series of tests are performed to confirm that the blood sample delivered to the genetic diseases evaluation center is fetal. Then, a short-term cell culture is performed in special media to multiply the cells.

From the cells obtained, the baby's chromosomes can be obtained, as well as DNA for the diagnosis of gene-level diseases. Since this method is applied in advanced gestational weeks, it is important that it is completed in a short time. Numerical evaluation of some chromosomes in a short time is possible with the Fluorescence Insitu Hybridization (FISH) method on the cells obtained.

When is cordocentesis performed?

Cordocentesis is performed after the 20th week of pregnancy. If the appropriate weeks for CVS (chorionic villus biopsy) or AS (amniocentesis) procedures have passed, genetic diagnosis can be made by cordocentesis.

Risks of Cordocentesis

Since the procedure is performed with special needles in the womb, it is thought to be harmful. However, the possibility of pregnancy loss is 1-2%. To avoid the risk of infection, the procedure must be performed by a specialist doctor and in a sterile environment with sterile materials. The possibility of the needle touching or damaging the baby is not possible with today's developing technology.

Can Cordocentesis Harm the Baby?

In the cordocentesis procedure, it is important to make sure that the physician who will perform the procedure is a specialist. In this case, cordocentesis does not cause any harm to the baby and pregnancy.

What is the difference between cordocentesis and amniocentesis?

The difference between cordocentesis and amniocentesis is that for amniocentesis, amniotic fluid is taken at 16 weeks or later. Cord blood for cordocentesis can be taken in pregnancies up to the 20th week. The important point is that the physician performing the procedure must be an expert in his/her job.

  • Amniocentesis is performed between the 16th and 18th weeks of pregnancy.
  • Cordocentesis is performed after the 20th week of pregnancy.
  • In amniocentesis, a sample is taken from the amniotic fluid that the baby is in.
  • In cordocentesis, a blood sample is taken from the baby's vein in the coronary cord between the baby and the mother.
  • In amniocentesis, long-term cell culture is performed and takes 15-20 days, while in cordocentesis, short-term cell culture is performed and takes 7-10 days.

Cordocentesis Prices

You can learn cordocentesis price information from WhatsApp line +90532 746 93 36 and +90312 217 32 26 for fixed line.

Update Date: 28.05.2022
Corporate
Editor
Genetic Diagnosis Center
Genetic Diagnosis Center
The content of the page is for informational purposes only.
Please consult your physician for diagnosis and treatment.

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Our center mainly provides services in the fields of genetic counseling, cytogenetics, molecular cytogenetics and molecular genetics. The problems of our patients who apply to our center, which are thought to have genetic causes, are helped by using up-to-date information and technology.

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Ankara Genetic Diagnosis Center
Genetics Laboratory
Ankara Genetic Diagnosis Center+90(312) 217 3226
Alacaatlı, Park Caddesi No:19 D:A/4 Cankaya Ankara Turkey
Email: info@ankaragenetik.com

We offer genetic analysis and clinical consultancy services at the highest technology and quality standards, using the most up-to-date scientific knowledge, diagnosis and treatment methods.

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